Exercise helps to battle prostate cancer, research says!

Exercise helps to battle prostate cancer, research says!

A recent study published in 'Medicine & Science in Sports & Exercise reported that myokines, a type of peptide released during exercise, can help to reduce and suppress tumour growth in patients with prostate cancer.

This study enrolled ten prostate cancer patients who had received androgen deprivation therapy (ADT) and underwent a 12-week exercise-based intervention. This intervention included protein supplementation, supervised resistance training and self-directed aerobic exercises.

Fasting blood was collected to evaluate serum myokines levels, and their effect on the growth of prostate cancer cells was assessed before and after the exercise-based intervention. In addition, Dual-energy x-ray absorptiometry (DXA) and one-repetition maximum (1RM) method were employed to determine body composition and muscle strength, respectively.

The findings reported a reduction in body weight, percent body fat and fat mass, with increased lean mass and strength. In addition, the serum myokines levels increased whereas DU145 Cell Index and growth rate of tumour cells decreased following post-intervention compared to baseline.

In conclusion, exercise significantly increases myokine expression, which leads to tumor-suppressive effects in prostate cancer patients.

SourceNCBI
Linkhttps://pubmed.ncbi.nlm.nih.gov/34559721/
Original Title of the ArticleMyokine Expression and Tumor-suppressive Effect of Serum following 12 Weeks of Exercise in Prostate Cancer Patients on ADT

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