Description
Benzigem 200/100 (Gemcitabine for injection) is a lyophilized powder available in a single use glass vial.
Generic Name– Gemcitabine hydrochloride
Drug Class – Antineoplastic agent
Gemcitabine is a pyrimidine nucleoside antimetabolite which exhibits anti-tumor activity against a variety of solid tumors including non-small cell lung cancer, pancreatic, bladder, ovarian and breast cancer. It acts by inhibiting ribonucleotide reductase and also competes with deoxycytidine triphosphate for incorporation into DNA. Both these processes results in inhibition of DNA synthesis, leading to apoptosis and cell death.
Dosage and Administration
Dosage Form and Strength
Benzigem 200/100 (Gemcitabine for injection) is a lyophilized powder available in a single use glass vial.
Gemcitabine is indicated:
Limitations of use:
Adverse reactions
Contraindications