Description
Fosamac 150 (Fosaprepitant for injection) is a lyophilized powder available as 150mg in single-dose vial for reconstitution.
Generic Name – Fosaprepitant
Drug Class- Antiemetic agent
Fosaprepitant is a prodrug formulation of aprepitant, an oral neurokinin-1 (NK1) receptor antagonist. It has been approved by FDA for prevention of acute nausea and vomiting associated with the use of highly and moderately emetogenic chemotherapeutic agents. It decreases the likelihood of vomiting induced by chemotherapeutic agents such as cisplatin by blocking substance P activity at NK1 receptors in the brain.
Dosage and Administration
Dosage Form and Strength
Fosamac 150 (Fosaprepitant for injection) is a lyophilized powder available as 150mg in single-dose vial for reconstitution.
Fosaprepitant is indicated in adults and pediatric patients 6 months of age and older, in combination with other antiemetic agents, for the prevention of:
Limitations of Use
Adverse Reactions
Contraindications