Irobenz 40/100 Liquid Injection

Generic Name- Irinotecan

Drug Class- Antineoplastic agent

Irinotecan is a DNA topoisomerase I inhibitor which is used as a chemotherapy agent against a variety of solid tumors, such as colorectal, pancreatic, ovarian, and lung cancers. It is also used in combination with other therapeutic agents against colorectal cancer as a first- or second-line treatment. It acts by inhibiting DNA topoisomerase I, an enzyme essential for relaxation of the DNA double helix during replication and transcription. Inhibition of topoisomerase I activity leads to disruption of DNA and RNA synthesis, which ultimately results in cell cycle arrest, apoptosis and cell death.